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Questions, experiences and reviews (20)

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is it ok to take vitamin B complex when you are on SINEMET (Levodopa-Carbidopa) therapy?
because ive read that vit B6 in the B complex breaks down the levodopa in the blood but there are also reports that with the combination of levo and carbidopa,it would prevent that effect.anybody care to enilghten me more about this?its for my mom coz she take the drug becoz of parkinson's symptoms.thanks!
sorceeress
08/08/08
Reply
  Found this to share, "If you are taking levodopa alone, you shouldn't take more than 5 mg per day of vitamin B 6 or it might impair the effectiveness of the drug. But if you use levodopa/carbidopa combinations that provide a total daily dose of at least 75 mg of carbidopa, this issue is not a concern."

So it sounds like if you are taking a dose of Sinemet that contains more than 75mg of Carbidopa, you should be fine. The worse that would happen is the Sinemet won't work as well. My doctor didn't mention anything to me about B vitamins - he did tell me that if I eat a meal with a lot of protein in it, to wait at least an hour before taking the Sinemet.
Sassy6gal
08/08/08
Which is more potent Sinemet or the generic equivalent of Carbidopa/Levodopa?
This drug is for parkinsonism
Chris
08/21/09
Reply
  generics cant be made and approved by the FDA unless theyre bioequivalent to the parent drug in some way, so carbidopa/levodopa and Sinemet have the same potency, contrary to public belief that generics are not as good as brand name.
sweet_ada_baby
08/23/09
Is anyone taking 4a risperidone/Risperdal, 4b fluoxetine/Prozac, or 4c levodopa & carbidopa/Sinemet or ANY OT
I would like to know when, why and if it worked? Also, if there any side effects?

Thank you all.
shine
09/24/06
Reply
  i am taking prozac,lithium,topomax,and should be on a benzaprine, all of mine work beautifully. i am bi-polar, and have severe migraines, and am being treated for anxiety. lithum gives you diahrea, benziprenes are addictive, prozac-no sides affects, topomax makes you sleepy
krystle e
09/24/06
My neurologist put me on Carbidopa 25mg Levodopa 250 for my Parkinson's symptoms. It contains aspartame?
I have CBD in the family of parkinson. I am want a equivalent treatment without this substance. This aspartane causes seizures.

01/07/11
Reply
  Aspartame is a no-no for any parkinson's or parkinsonian patient. You were probably put on Parcopa or something similar. Sinemet - the non-generic- does not contain aspartame but is not available as a chewable tablet.

I think you have already gotten the answer. Have either the neurologist or the pharmacist check all 25/250 generics and brand-name dopaminergics to see which ones do not contain aspartame. I have done a quick look and cannot find any.

The problem is that aspartame is commonly added to the chewable or orally disintegrating versions of this medication when patients are having the typical swallowing issues.

I am also surprised that you are on a dopaminergic for Corticobasal Degeneration (CBD) because the symptoms do not commonly respond to dopaminergic treatment, although some have been successful. Aside from the seizures, have you noticed any positive effects?
http://www.ucsfhealth.org/conditions/corticobasal_degeneration/treatment.html

Have you and your doctor thoroughly discussed your treatment plan and your options? Do not be afraid to be aggressive. CBD requires that you be proactive in your care and treatment.

I just went hunting for nutritional supplement support for CBD and found the article below. It is worth a read if you haven't done so already. I'm only familiar with some of the protocols discussed but...who knows...
http://www.perpetualcommotion.com/a/Patricias_Protocol.html
Mags
01/07/11
My neurologist put me on Carbidopa 25mg Levodopa 250 for my Parkinson's symptoms. It contains aspartame?
I have CBD in the family of parkinson. I am want a equivalent treatment without this substance. This aspartane causes seizures.
revyrev
01/07/11
Reply
  Aspartame is a no-no for any parkinson's or parkinsonian patient. You were probably put on Parcopa or something similar. Sinemet - the non-generic- does not contain aspartame but is not available as a chewable tablet.

I think you have already gotten the answer. Have either the neurologist or the pharmacist check all 25/250 generics and brand-name dopaminergics to see which ones do not contain aspartame. I have done a quick look and cannot find any.

The problem is that aspartame is commonly added to the chewable or orally disintegrating versions of this medication when patients are having the typical swallowing issues.

I am also surprised that you are on a dopaminergic for Corticobasal Degeneration (CBD) because the symptoms do not commonly respond to dopaminergic treatment, although some have been successful. Aside from the seizures, have you noticed any positive effects?
http://www.ucsfhealth.org/conditions/corticobasal_degeneration/treatment.html

Have you and your doctor thoroughly discussed your treatment plan and your options? Do not be afraid to be aggressive. CBD requires that you be proactive in your care and treatment.

I just went hunting for nutritional supplement support for CBD and found the article below. It is worth a read if you haven't done so already. I'm only familiar with some of the protocols discussed but...who knows...
http://www.perpetualcommotion.com/a/Patricias_Protocol.html
Mags
01/07/11
Cerebral palsy-looking information?
Hi
My cousin is born with Cereberal palsy .CP is discovered after 30 days of his birth .he is premature and now he is 8 year old.He is under gone for many surgeries and physio therapy .Surgery was mainly near to the hip to loose the rigid muscles.Still he does not walk and mentally he is a perfect kid.
Recently one of the doctor suggested to give Levodopa and carbidopa medicines..
No idea will this cure..Is CP patient can walk after certain age?
sandy
02/27/09
Reply
  you can know more about CP at this medical blog
http://teensandhealth.blogspot.com/
adam
02/28/09
What was these "cocktail" of drugs indicated for?
My co-worker are taking "cocktail" of drugs.

These are the medications she is taking; Biperiden, Sertraline and Carbidopa+Levodopa.

What might be the doctor's diagnosis?
I know it is not my duty to ask about her personal life but it is affecting her job.
I am his immediate superior and for past few days she is not being productive anymore.
And she keeps on missing deadline.
She is restless, uncooperative, seem depressed and detached from the rest of her co-worker.

02/10/11
Reply
  biperiden carbidopa +levodopa anti parkinson medications
sertraline=selective serotonin reuptake inhibitor used for depression mainly also used for obsessive compulsive disorder, panic disorder, post-trauma stress, premenstrual dysphoric disorder (PMDD) or social anxiety.
pecola princepessa
02/10/11
What was these "cocktail" of drugs indicated for?
My co-worker are taking "cocktail" of drugs.

These are the medications she is taking; Biperiden, Sertraline and Carbidopa+Levodopa.

What might be the doctor's diagnosis?
I know it is not my duty to ask about her personal life but it is affecting her job.
I am his immediate superior and for past few days she is not being productive anymore.
And she keeps on missing deadline.
She is restless, uncooperative, seem depressed and detached from the rest of her co-worker.
Gener S.
02/10/11
Reply
  biperiden carbidopa +levodopa anti parkinson medications
sertraline=selective serotonin reuptake inhibitor used for depression mainly also used for obsessive compulsive disorder, panic disorder, post-trauma stress, premenstrual dysphoric disorder (PMDD) or social anxiety.
pecola princepessa
02/10/11
Sertraline and Hydrocodone and love to eat a grapefruit for breakfast?
I am also taking Crestor, Protonix, Folic Acid, Cyclobenzaprine, Sulfasalazine, Remicade , Furosemide, Klor-Con, Carbidopa-Levodopa and Methotrexate along with the Sertraline and Hydrocodone. Will eating grapefruit for breakfast every day cause me any serious issues? If so, please let me know what kind of issues and which meds would be involved. Thank you.
dar5507
04/12/11
Reply
  The chemical composition in the grapefruit will increase the effect and pain killing properties of the Hydrocodone. I learned this from a drug counselor, but I have no idea if the grapefruit has any other effects on your other meds. You may want to consult a pharmacist because he could quickly and accurately find out if there may be any negative or life threatening side effects with a few quick clicks of his computer. Good luck! P.S. I love grapefruit, yum!
Connie D
04/12/11
What is wrong with my legs?
About 5 years ago I was diagnosed with RLS (Restless Legs Syndrome) and have been on numerous medications. I am currently taking Carbidopa 25mg/Levodopa 100mg. This is not working so well. I am beginning to wonder if I have been properly diagnosed. I have researched the web extensively and have consulted two different doctors. My concern is that none of my research has mentioned anything about "popping" of the joints in my legs. I have the usual RLS symptom of the urge to move my legs but I have noticed that when this symptom occurs it is accompanied by "popping" of all the joints in my feet and legs. I have also noticed that at the same time the blood veins in my legs are enlarged. On the rare occassions that I do not have the urge to move my legs I do not have the other symptoms either. Anyone have any ideas?
JRandy
04/05/08
Reply
  I would read about all of the "numerous" meds you have taken for what was diagnosed as RLS. There is the possibility that one or more of the meds may have caused or contributed to the popping. All pharmaceutical medications have negative side effects of various forms. Many of the side effects of each medication will be listed in the paperwork included with your prescriptions or you can ask your pharmacist for it.

There are ways to "treat" RLS with medication if your goal is just to treat it. I prefer to heal problems instead of treating them. It just doesn't make sense to me to make the symptoms go away yet leave the underlying cause of the problem unresolved or most generally even undetermined. That's kind of like driving your car and your oil light comes on, so instead of checking your oil and adding more oil, you open up the dash and unplug the light. That is definitely going to lead to some future problems. Our bodies use symptoms as a means of communicating to us that there is a problem we need to look at. If you have symptoms similar to that of what your doctor deemed to be RLS you should want to know why you have those symptoms. What is the underlying cause? I would definitely look into your diet, even start a log book of the foods you eat and also log the level of your legs wanted to move. You might just find that your symptoms are increased or decreased with certain foods or certain food combinations.

Additionally, I would recommend that you seek out a licensed accupuncturist who performs what is called a full elemental diagnosis. The accupuncture will be customized especially for you and will be to treat your entire body.
No doubt there will be people who tell you this is crazy or call it some crack pot fake medicine. To that I say it is your body. You will live with the decisions you make. It would seem rather narrow minded to discount something as being fake, due to a lack of understanding by those casting the stones.
William E
04/05/08
Can I increase my Rheumatoid Factor in days?
I need some serious expertise from future Nobel Prize winners...
This may be a weird question but I wish to increase my Rheumatoid Factor in a short period of time because that would allow me to waive my country's stupid mandatory military service. My RA was tested near 37 before, but somehow it came down to 10. I am not sure if the drop is due to the different methods of tests or it just comes down for other reasons.
My father has Parkinson's disease so he has some medications such as Amantadine, Levodopa, Carbidopa, Entacapone, and some anti-depressed medications. Would any of the above medicines help INCREASE RA factor if a normal person takes it?
My fingers do hurt once in a while, but need a positive RA factor result to back up and therefore waive the mandatory militaryservicee.

Future Nobel Prize winners, please help~~~

10/06/09
Reply
  discuss this in detail with your rheumatologist.
nancy jo
10/06/09
Can I increase my Rheumatoid Factor in days?
I need some serious expertise from future Nobel Prize winners...
This may be a weird question but I wish to increase my Rheumatoid Factor in a short period of time because that would allow me to waive my country's stupid mandatory military service. My RA was tested near 37 before, but somehow it came down to 10. I am not sure if the drop is due to the different methods of tests or it just comes down for other reasons.
My father has Parkinson's disease so he has some medications such as Amantadine, Levodopa, Carbidopa, Entacapone, and some anti-depressed medications. Would any of the above medicines help INCREASE RA factor if a normal person takes it?
My fingers do hurt once in a while, but need a positive RA factor result to back up and therefore waive the mandatory militaryservicee.

Future Nobel Prize winners, please help~~~
Ray Ray
10/06/09
Reply
  discuss this in detail with your rheumatologist.
nancy jo
10/06/09
What to do if taking levodopa (L-dopa) for Parkinson's Disease cause nausea and vomiting?
Any ways to prevent vomitting after taking levodopa (L-dopa) for Parkinson's Disease?
earthcosmic2
09/22/08
Reply
  Of course it is always recommended to be taken with food. But more helpful are the combination drugs available. Combination of levodopa-benserazide, (Madopar,) works well for some. More commonly used is, levodopa-carbidopa, (Sinemet, Atemet.) The levodopa-caridopa combination has a new FDA approved oral med that dissolves on the tongue and has shown to be effective.

Hope this is informative.
Desi
09/22/08
I take carpidopa/levodopa for RLS is it for that or parkinsons disease?
missinnh05
09/30/08
Reply
  Carbidopa/levodopa is used sometimes to treat severe restless leg syndrome, and is a common medication for parkinson's disease.
Desi
09/30/08
how soon will I begin feeling the effects of levodopa?
saint
08/23/06
Reply
  If you have Parkinson's Disease, the effect should be fairly rapid. You should certainly notice something before 2 weeks. More likely by 1 week.
Frito
08/23/06
What does levodopa do?
Im doing a report on parkinsons and need help!!! Any other meds and their costs would help.
Thx!!!
Hope G
02/01/08
Reply
  Dopaminergics:

Drugs used to replace or mimic the actions of dopamine.

Sinemet

Chemical name: Carbidopa-Levodopa

Indications: Helps all symptoms of PD. It is the primary anti-Parkinson drug. It is a combination of levodopa and carbidopa. Carbidopa allows levodopa to enter the brain, where it is converted to dopamine.

Dosages: Expressed as fractions, with top number referring to amount of carbidopa and the bottom number of levodopa, in milligrams. Common dosages are 10/100, 25/100, 25/250.

Range of daily dosage: 75-150 mg carbidopa; 75-1,000 mg levodopa.
Rex B
02/02/08
Since faba bean contains levodopa should it be avoided by schizophrenics & eaten by Parkinson patients?
Faba fan
02/14/10
Reply
  While the amount in one serving of fava beans (vicia faba) might make no difference in either schizophrenics or PwPs, a regular diet which included them would.

Fava Beans or velvet beans are indeed used as a treatment for Parkinson's disease. Mucuna puriens are really levodopa. It is just that they have a 5,000 year ayruvedic medical history of usage for Parkinson's disease (kampavata).

One problem is dosage. Just as with levodopa, you would begin slowly and titrate up to an effective "dose" and that can be much more difficult with a food product especially one which you might need to eat 2-4 times a day. Be aware that if taking B6 as well the proper dosage balance with the levodopa needs to be learned as B6 can decrease its effectiveness.

Fava beans do indeed have a medicinal benefit in the treatment of PD and thus far it does not appear that they have the same "wearing off" effect. If they do, there are also natural supplements which can be added.

The balance in schizophrenia is rather delicate, but one serving will not create a Hannibal Lecter.

One serving would, however, be sufficient to cause a problem in someone with Favism or G6PD deficiency.
http://www.wisegeek.com/what-is-favism.htm
http://www.sciencedaily.com/releases/2007/03/070313114502.htm
Mags
02/14/10
does anyone know if and what side effectcs are to suddenly stop taking tramadol and carbidopa?
these are both pain meds that I have been on for quite some time.1 and 2 yrs. 1 dose is 3 x a dayand the other is 1/2 @ night. I am ttc. (6 mo.) I feel this may be stopping me from that. thanks.
cmf242004
03/13/07
Reply
  Why do you have to stop suddendly? it is usually not dangerous to do so, but you can feel bad.Why not get off slower -like 0.5 tablets every 3-4 days.You will enventually get there anyway.
All the best

marya
marya
03/13/07
What are some of the ways to lessen hallucinations induced by levodopa in patients with Parkinson's disease?
Visual and auditory hallucinations have become worse due to the drug's side effects.
Archie
09/03/06
Reply
  This may get started on an answer. I wish I could be more helpful.
sunday siren
09/03/06
Is Nitric Oxide a good supplement for People with parkinsons.?
I dont see any contra indications. Force Factor (nitric Oxice) says it boosts energy, increase sternght, promotes health and promotes recovery. I take prescription meds(carbidopa/Levodpa)
Chris
08/27/10
Reply
  Arginine is the precursor to NO, and it does have some benefit to some heart conditions - however, it has also been shown to increase heart attack risk in some studies. Based on that alone, I would discuss the matter with the individuals cardiologist....and I assure you, cardiologists would know all about arginine....

However, that said - very few people are lacking in arginine - dietary sources of it are rather common and plentiful
Tink
08/27/10

Consumer feedback Disclaimer
Status updates

nickelamshah: What's levodopa?
eykamajor: @nickelamshah levodopa? what's that?
Dr_Hattivatti: The most common early side effects of lovodopa/carbidopa are hallucinations, dizziness, headache, and agitation.